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Targeted Metabolomics

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We perform targeted metabolomics application of metabolomics analysis to specific classes of compounds. Custom developed LC-MS methods are designed to selectively collect information regarding group(s) of related metabolites extracted from biological fluids. Metabolite identification is performed by interpreting high resolution MS data and low resolution MS/MS fragmentation data (if applicable), searching against databases and comparing with authentic compounds.

Metabolic oxidation regulates embryonic stem cell differentiation Nature Chemical Biology
Yanes O1, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G.
2010 Jun;6(6):411-7. doi: 10.1038/nchembio.364. Epub 2010 May 2