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Welcome to the web home of the Vincent Coates Foundation Mass Spectrometry Laboratory, a University-wide VPDoR resource. The laboratory is named in honor of a generous gift from Vincent and Stella Coates to support the mass spec & proteomics facility as a shared core resource. It is a BioX core, embodying the Bio-X spirit of interdisciplinary communication and collaboration. It is also partially supported as the Proteomics Shared Resource of the Stanford Cancer Institute, and is active in Stanford C-ShaRP initiatives. The laboratory's expertise and support are available to researchers throughout Stanford University & Medical Center and worldwide.
Beyond making available state-of-the-art, user-friendly facilities and services, the laboratory enables education, methods development, and new applications development, designed to meet the rapidly evolving needs of researchers. Due to the essential information that mass spectrometry provides to researchers in the fields of the physical and life sciences, medicine, and engineering, the laboratory serves as an “intellectual watering hole” at the crossroads of diverse disciplines.
At this time, we have in operation a MALDI-TOF, GC/MS and eleven LC/MS systems -- one single quad, four triple quads, one quadrupole-time of flight, two tribrid Orbitraps and three quadrupole-Orbitraps. Software resources include instrument-specific packages Xcalibur, MassLynx, Mass Hunter; proteomics software Byonic, Byologic, Protein Discoverer, Spectronaut; and other tools TraceFinder, LipidSearch, Compound Discoverer, QuanLynx, Skyline, Remote Analyzer.
Mass spec and proteomic services include an open access lab for trained users with GC/MS, LC/MS, high resolution LC/MS, and MALDI-TOF instruments. Get in-depth hands-on training to access more advanced platforms. Work with our staff on intact protein analysis, targeted quantitation, drug discovery support, pathway analysis, metabolomic profiling, protein interactions and structural studies, quantitative proteomics, FFPE tissue analysis, labeled and label-free proteomics, and more. Please contact SUMS to discuss these and other custom projects including experiential learning and new application development.
Please check back regularly for news and announcements. It is our hope that these pages will be a valuable resource to you.