SUMS-RAS 2024

Connecting Innovation and Science

Thursday, October 17th 2024

9 am - 4 pm

in person at the Stanford Health Care rooftop Assembly Hall

A free symposium for mass spectrometry users, researchers, and explorers! Join Stanford's mass spectrometry community in person to learn about exciting mass spec research and resources, and to build valuable connections with fellow scientists.

Call for abstracts!

Project Pitch Competition

The Project Pitch Competition invites students and postdoctoral scholars to give a brief 5-minute pitch on a research project they would like to complete using the resources available at SUMS. The successful participants will be given up to $1000 of funding to carry out their experiment at SUMS. Interested candidates should provide an abstract at the link below:

Submit abstract

SUMS-RAS 2024: Connecting Innovation and Science

Time	Event:
9:00 AM	Breakfast
9:25 AM	Welcome
9:30 AM	Project Pitch Competition
10:30 AM	Dr. Ruth Huttenhain \| Assistant Prof., Stanford University : Signaling of G Protein-Coupled Receptors (GPCRs) Across Time and Space
11:00 AM	Exhibits & Refreshments break
11:30 AM	Dr. Matt Bush \| Associate Prof., University of Washington
12:00 PM	Lunch & Exhibits
1:00 PM	Dr. Autumn Qiu \| Assistant Prof., Michigan State University: Visualizing Gut-microbe Interactions with Mass Spectrometry Imaging
1:30 PM	Career Panel: John Stults, Genentech \| Fiona McAllister, Calico Life Sciences \| Chris Adams, Rezo Therapeutics \| Chris Crittenden, Genentech \| Jim Pesavento, St. Marys College \| Mimi Roy, Biotech Consultant
2:30 PM	Career booth discussions & Coffee break
3:00 PM	Project Pitch Competition Awards Presentation
3:15 PM	Drinks Reception
4:30 PM	Close

Introducing this year's speakers...

**Dr. Matt Bush, Ph.D.**
*Associate Professor, Department of Chemistry*
*University of Washington*

Matt Bush pursued his PhD with Evan Williams and Richard Saykally at the University of California, Berkeley. During that time, he used IR laser spectroscopy and FT-ICR mass spectrometry (MS) to investigate zwitterion formation and ion solvation. This training in high-performance MS and physical chemistry laid the groundwork for his continued pursuits using gas-phase techniques to investigate the structures and interactions of biomolecules. He then joined the laboratory of Carol Robinson FRS DBE at the University of Cambridge and the University of Oxford, during which time he used ion mobility MS to characterize the structures of biomolecules, large and small. He joined the chemistry faculty at the University of Washington in 2011, where he also participates in several interdisciplinary programs. His research group develops MS-based approaches for elucidating the structures, stabilities, and dynamics of biomolecules. They apply those approaches to a wide range of biological systems, especially those involved in protein homeostasis.

**Dr. Ruth Huttenhain, PhD**
*Assistant Professor*
*Department of Molecular & Cellular Physiology*
*Stanford University*

Ruth is an Assistant Professor in the Department of Molecular and Cellular Physiology at Stanford. She obtained her PhD from ETH Zurich, Switzerland, where she developed high-throughput, large-scale targeted mass spectrometric approaches. During her postdoc at UCSF, Ruth extended her expertise in quantitative mass spectrometry to study dynamics of interaction networks. She pioneered a proximity labeling-mass spectrometry approach that simultaneously captures the precise temporal remodeling and spatial organization of proximal protein networks with a focus on G protein-coupled receptors (GPCRs). Ruth’s group at Stanford deciphers how GPCRs decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. She exploits quantitative proteomics to capture the spatiotemporal organization of signaling networks combined with functional genomics to study their impact on physiology. As a Co-Chair of the Human Proteome Organization Early Career Researcher (ECR) Committee Ruth is committed to promote ECRs and increase the visibility of their research.

**Dr. Autumn Qiu, Ph.D.**
*Assistant Professor, Department of Chemistry*
*Michigan State University*

Prof. Tian (Autumn) Qiu completed her BS in Chemistry at Peking University in 2012 and PhD in Chemistry at University of Minnesota in 2018. Her PhD work focused on understanding nanotoxicity mechanisms to environmental bacteria in the laboratory of Prof. Christy Haynes as part of the Center for Sustainable Nanotechnology. She was awarded in 2018 as a Beckman Postdoctoral Fellow at University of Illinois at Urbana-Champaign and worked in Profs. Jonathan Sweedler, Nathan Schroeder, and Huimin Zhao's labs on exploring the sources, biodistribution and functions of D-amino acids in the microbiome-gut-brain axis using mass spectrometry as well as microbial and animal models including rodents and Caenorhabditis elegans. She started as an Assistant Professor in Chemistry at Michigan State University in Fall 2022. Her research group at MSU studies the molecular interactions between environmental contaminant exposure, microbial metabolism, and host animal response using mass spectrometry, particularly MS imaging, in combination with animal models, biochemical analysis, and toxicological assays.

Meet the career panelists!

**Dr. Fiona McAllister, Ph.D.**
*Principal Investigator, Proteomics*
*Calico Life Sciences*

Fiona is a Principal Investigator in Proteomics at Calico Life Sciences. Fiona pursued a PhD in Proteomics at the University of Edinburgh in Prof. Perdita Barran’s lab with industry sponsorship from Procter & Gamble. She continued her research as a post doctoral fellow at Harvard Medical School in Prof. Steven Gygi’s lab. After moving to the Bay area, Fiona worked at Stanford University in the Chemical & Systems Biology department and gained experience working with cerebral spinal fluid, important for neurodegenerative disease biomarker research. Fiona subsequently joined Caprion Biosciences, where her work focused on biomarker research for neurodegeneration. In 2016, Fiona joined Calico Life Sciences to lead the proteomics technology lab. Calico, an Alphabet-founded company, has at its core mission the goal of harnessing advanced technologies and model systems to increase our understanding of the biology that controls human aging. Fiona’s lab at Calico develops and applies mass spectrometry proteomics methods for aging research and drug development.

**Dr. John Stults, Ph.D.**
*Staff Scientist - Technical Development, Analytical Development and Quality Control*
*Genentech*

John Stults joined Genentech in 1987 to lead the newly-formed Research mass spectrometry group, acquiring a cutting-edge four-sector MS to study proteins and their post-translational modifications. His lab developed numerous protein analysis methods including Peptide Mass Fingerprinting, which laid a foundation for the field of proteomics and was recognized by a joint 2002 Distinguished Contribution in Mass Spectrometry Award from the American Society for Mass Spectrometry (ASMS). After 4 years at a start-up company, John returned to Genentech in 2006 to lead the Analytical Operations department in what is now Pharma Technical Development. Since then, he has held positions as Director of Protein Analytical Chemistry and Chair of the Analytical Review Committee, as well as Associate Editor of Molecular & Cellular Proteomics. As a result of his substantive contributions to Genentech and attainment of the highest levels of scientific achievement as recognized by the international scientific community, John has earned the distinction of being named a Genentech Fellow.

**Dr. Chris M. Crittenden, Ph.D.**
*Principal Scientist, Structure Elucidation Group*
*Genentech*

**Dr. Mimi Roy, Ph. D**
*Protein Chemist*
*Biotech Consultant*

Mimi Roy, Ph. D. is a protein chemist trained in protein/DNA design, mass spectrometry, analytical chemistry and bioinformatics, and currently consults for multiple biotech companies. With >25 years of experience in biologics production/analytics, omics-based analytics and CMC, she was most recently held the position of SVP, TechOps at Grace Science where she was responsible for viral vector production to supply a Phase1 clinical trial (ongoing) for NGly1 deficiency, and prior to that ran the Scientific part of Resilience’s R&D Organization in San Diego as VP, Process and Platform. Mimi learned gene therapy beginning at BioMarin in 2015 as Head of Analytical and has contributed to successful approval of many therapeutics from small molecules and proteins to viral vectors/gene therapy. Mimi is passionate about improving AAV vectors and leading CMC strategies to deliver safe and efficacious treatments to rare disease patients.

**Dr. Chris Adams, Ph.D.**
*Director of Proteomics*
*Rezo Therapeutics*

Chris Adams is Director of Proteomics at Rezo. Chris has over 15 years experience in mass spectrometry-based proteomics in both industry and academia. Prior to joining Rezo, Chris was the Director of Bioinformatics Business Development at Bruker Corporation. Chris held the role of Director of Proteomics at Stanford University Mass Spectrometry, leading the SUMS and Stanford Cancer Center proteomics core, where his work led to more than 40 publications. Chris received a B.S in Biochemistry from California Polytechnic State University, San Luis Obispo and a Ph.D. in Biological and Medical Mass Spectrometry from Uppsala University, Sweden.

**Dr. Jim Pesavento, Ph.D.**
*Associate Professor and Chair of the Biology Department*
*Saint Mary’s College of California*

Jim Pesavento attended the University of Illinois, Urbana-Champaign (UIUC) and earned double degrees in Honors Biology and Biochemistry. Strongly influenced by his undergraduate research experience at UIUC, he decided to continue his education there by entering the Biophysics and Computational Biology graduate program. After completing his PhD, a post-doctoral research fellowship brought him to the University of California, Berkeley and finally to Saint Mary’s College of California where he is currently an Associate Professor and Chair of the Biology Department. His strong commitment to undergraduate teaching and biochemistry research has earned him several National Science Foundation grants and Saint Mary’s College 2022 Early Career Award. When not teaching or research mentoring, he enjoys playing ‘beer league’ ice hockey and ‘getting owned’ on Roblox by his 11-year-old son.

How to get in touch with the SUMS experts

Connecting Innovation and Science

Project Pitch Competition

SUMS-RAS 2024: Connecting Innovation and Science

Introducing this year's speakers...

Meet the career panelists!

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