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Featured Paper        
  "A Double-Vented Tetraphasic Continuous Column Approach to MudPIT Analysis on Long Capillary Columns Demonstrates Superior Proteomic Coverage" Andrew W. Guzzetta, Allis S. Chien. Journal of Proteome Research, 2005, 4, 6, 2412-2419. JPR abstract
               

   
Posters displayed in Keck building atrium

Posters & Presentations

"Stanford University Mass Spectrometry" Allis S. Chien, Christopher M. Adams, Karolina M. Krasinska, Theresa M. McLaughlin. Presented at ABRF 2008, Salt Lake City, UT; Facility poster 16. download .pdf

"LC-MS and LC-MS/MS analysis of bile from mice infected with Listeria monocytogenes" Karolina M. Krasinska, Jonathan W. Hardy, Lindsay Comeaux, Christopher Contag, Allis S. Chien. Presented at the 55th ASMS Conference on Mass Spectrometry, Indianapolis, IN, 2007; ThP-311. download .pdf

"Practical Aspects of Long Column Capillary Chromatography " Andrew W. Guzzetta, Allis S. Chien. Presented at the New Objective Users' Meeting, ABRF 2007, Tampa, FL. download .pdf

"Proteomic Investigations using a Double-vented Tetraphasic Continuous Column Approach to MudPIT Analysis" Andrew W. Guzzetta, Allis S. Chien. Presented at the 232nd National Meeting of the American Chemical Society, San Francisco, CA, September 2006; ANYL 23. download .pdf

"Simultaneous LC-MS/MS Quantitation of Sulforaphane and its Metabolites: Investigation of Sulforaphane Metabolism in Rat Tissues" Karolina M. Krasinska, Suvarna Bhamre, James D. Brooks, Allis S. Chien. Presented at the 54th ASMS Conference on Mass Spectrometry, Seattle, WA, 2006; MP01-018. download .pdf

"LC-MS/MS Detection of Monosaccharides from Yeast Selected for Xylose Consumption" Lindsay M. Comeaux, Boris U. Stambuk, R. Paul Levine, Gavin J. Sherlock, Allis S. Chien. Presented at the 54th ASMS Conference on Mass Spectrometry, Seattle, WA, 2006; ThP17-296. download .pdf

"Rapid Mapping of Protein Conformational Landscapes by Automated Data Acquisition & Analysis of Multiplexed HXMS Timecourses" Allis S. Chien, Judith Frydman, Andrew D. Miranker, Sheila S. Jaswal. Presented at the 54th ASMS Conference on Mass Spectrometry, Seattle, WA, 2006; ThP29-543. download .pdf

"Biological Applications of Q-Tof Mass Spectrometry in an Academic Core Facility " Allis S. Chien. Presented at the Waters Q-Tof Users' Meeting, April 24-25, 2006, Monterey, CA. download .pdf

"Benefits and Practical Aspects of Long Column Chromatography" Allis S. Chien, Andrew W. Guzzetta. Webinar, Eksigent Technologies, March 8, 2006. archived webinar

"Cleaning Up MudPIT: Triphasic Traps and Long Columns" Allis S. Chien, Andrew W. Guzzetta. Presented at the Eksigent Users' Meeting, ABRF 2006, Long Beach, CA. download .pdf

"Vented Column Technology Applied to Proteomic MudPIT Analysis on Long Capillary Columns" Andrew W. Guzzetta, Allis S. Chien. Presented at the 53rd ASMS Conference on Mass Spectrometry, San Antonio, TX, 2005; ThOEpm 3:20. download .pdf

"Investigation of Low Molecular Weight Serum Components by an Automated Two-Stage NanoLC-MS Method" Allis S. Chien, Andrew W. Guzzetta. Presented at the 53rd ASMS Conference on Mass Spectrometry, San Antonio, TX, 2005; WP11-170. download .pdf

"Quantitative Analysis of Sulforaphane and its Metabolites in vivo" Karolina M. Krasinska, Suvarna Bhamre, James Brooks, Allis S. Chien. Presented at the 53rd ASMS Conference on Mass Spectrometry, San Antonio, TX, 2005; WP03-040. download .pdf

"Automated Direct Monitoring of H/D Exchange Reactions for Mapping Conformational Landscapes of Proteins" Allis S. Chien, Sheila S. Jaswal. Presented at the Advion Users' Meeting, ASMS 2005, San Antonio, TX. download .pdf

"An Evaluation of Extended Length Reverse Phase Capillary Columns for Simple LC/MS Peptide Mapping and for Complex Proteomic Separations" Andrew W. Guzzetta, Allis S. Chien. Presented at the 52nd ASMS Conference on Mass Spectrometry, Nashville, TN, 2004; WoAam 11:15. download .pdf

"Ammonium Sulfate Precipitation as a Novel First Dimension in the Multidimensional Analysis of a Complex Proteome" Allis S. Chien, Andrew W. Guzzetta. Presented at the 52nd ASMS Conference on Mass Spectrometry, Nashville, TN, 2004; ThPW-469. download .pdf

"Proteome Profiling of Corynebacterium glutamicum by 2-D PAGE and LC-MS/MS" Allis Chien, Andrew Guzzetta, Yoshifumi Shinoda, Masayuki Inui, Hideaki Yukawa. Presented at the Stanford Biotechnology Conference, Stanford, CA, 2003. download .pdf

"Mass Spectrometry & Stanford Chemistry" Allis Chien. Presented to the Stanford Dept. of Chemistry, Stanford, CA, 2003. download .pdf

Selected papers

75) "Proteomic identification of tmRNA substrates" Sue-Jean Hong, Faith H. Lessner, Elisabeth M. Mahen, Kenneth C. Keiler. PNAS, 2007, 104, 43, 17128-17133. DOI: 10.1073/pnas.0707671104

74) "Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans" Sam G. Gu, Julia Pak, Sergio Barberan-Soler, Mustapha Ali, Andrew Fire, Alan M. Zahler. RNA, 2007, 13, 1492-1504. DOI: 10.1261/rna.581907

73) "Synthesis of Nitric Oxide Reductase Active Site Models Bearing Key Components at Both Distal and Proximal Sites" James P. Collman, Ying Yang, Richard A. Decreau. Organic Letters , 2007, 9, 15, 2855-2858. DOI: 10.1021/ol071007p

72) "Do Ligand Binding and Solvent Exclusion Alter the Electrostatic Character within the Oxyanion Hole of an Enzymatic Active Site" Paul Sigala, Aaron T. Fafarman, Patrick E. Bogard, Steven G. Boxer, Daniel Herschlag. Journal of the American Chemical Society, 2007, 129, 12104-12105. DOI: 10.1021/ja075605a

71) "Salicylic Acid, Yersiniabactin, and Pyoverdin Production by the Model Phytopathogen Pseudomonas syringae pv. tomato DC3000: Synthesis, Regulation, and Impact on Tomato and Arabidopsis Host Plants" Alexander M. Jones, Steven E. Lindow, Mary C. Wildermuth. Journal of Bacteriology , 2007, 189, 19, 6773-6786. DOI: 10.1128/JB.00827-07

70) "Safeners coordinately induce the expression of multiple proteins and MRP transcripts involved in herbicide metabolism and detoxification in Triticum tauschii seedling tissues" Qin Zhang, Fangxiu Xu, Kris N. Lambert, Dean E. Riechers. Proteomics, 2007, 7, 8, 1261-1278. DOI: 10.1021/ol701950d

69) "delta-Sulfone Formation Through Rh-Catalyzed C-H Insertion" Scott A. Wolckenhauer, A. Sloan Devlin, J. Du Bois. Organic Letters , 2007, 9, 21, 4363-4366. DOI: 10.1002/pmic.200600423

68) "Aerobic Alcohol Oxidation with Cationic Palladium Complexes: Insights into Catalyst Design and Decomposition" Nicholas R. Conley, Liezel A. Labios, David M. Pearson, Charles C. L. McCrory, Robert M. Waymouth. Organometallics, 2007, 26, 23, 5447-5453. DOI: 10.1021/om700492n

67) "The END Network Couples Spindle Pole Assembly to Inhibition of the Anaphase-Promoting Complex/Cyclosome in Early Mitosis" Kenneth H. Ban, Jorge Z. Torres, Julie J. Miller, Alexei Mikhailov, Maxence V. Nachury, Jeffrey J. Tung, Conly L. Rieder, Peter K. Jackson. Developmental Cell, 2007, 13, 1, 29-42. DOI: 10.1016/j.devcel.2007.04.017  

66) "Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p" Daqi Tu, Wei Li, Yihong Ye, Axel T. Brunger. PNAS, 2007, 104, 40, 15599-15606. DOI: 10.1073/pnas.0701369104  

65) "Structure–activity relationships of semisynthetic mumbaistatin analogs" Taek Soon Lee, Abihirup Das, Chaitan Khosla. Bioorganic & Medicinal Chemistry , 2007, 15, 15, 5207-5218. DOI: 10.1016/j.bmc.2007.05.019  

64) "Acetylation of Smad2 by the Co-activator p300 Regulatesctivin and Transforming Growth Factor beta Response" Andrea W. Tu, Kunxin Luo. Journal of Biological Chemistry, 2007, 282, 29, 21187-21196. DOI: 10.1074/jbc.M700085200  

63) "Organic Spirocyclic Initiators for the Ring-Expansion Polymerization of beta-Lactones" Wonhee Jeong, James L. Hedrick, Robert M. Waymouth. Journal of the American Chemical Society, 2007, 129, 27, 8414-8415. DOI: 10.1021/ja072037q

62) "Intramolecular Single-Turnover Reaction in a Cytochrome c Oxidase Model Bearing a Tyr244 Mimic" Collman, James P.; Decreau, Richard A.; Yan, Yilong; Yoon, Jungjoo; Solomon, Edward I. Journal of the American Chemical Society, 2007, 129, 18, 5794-5795. DOI: 10.1021/ja0690969

61) "Syntheses of Hemoprotein Models that can be Covalently Attached onto Electrode Surfaces by Click Chemistry" Decreau, Richard A.; Collman, James P.; Yang, Ying; Yan, Yilong; Devaraj, Neal K. Journal of Organic Chemistry, 2007, 72, 8, 2794-2802. DOI: 10.1021/jo062349w

60) "Investigation of Early Tailoring Reactions in the Oxytetracycline Biosynthetic Pathway" Wenjun Zhang, Kenji Watanabe, Clay C. C. Wang, Yi Tang. Journal of Biological Chemistry , 2007, 282, 35, 25717-25725. DOI: 10.1074/jbc.M703437200

59) "A novel chemiluminescent substrate for detecting lactamase" Tabassum Naqvi, Rajendra Singh. Molecular BioSystems , 2007, 3, 431-438. DOI: 10.1039/b705898p

58) "A Cytochrome c Oxidase Model Catalyzes Oxygen to Water Reduction Under Rate-Limiting Electron Flux" Collman, James P.; Devaraj, Neal K.; Decreau, Richard A.; Yang, Ying; Yan, Yi-Long; Ebina, Wataru; Eberspacher, Todd A.; Chidsey, Christopher E.D. Science, 2007, 315, 5818, 1565-1568. DOI: 10.1126/science.1135844. abstract

57) "Bioassay-Guided Evolution of Glycosylated Macrolide Antibiotics in Escherichia coli" Lee, Ho Young; Khosla, Chaitan. PLoS Biology, 2007, 5, 2, e45. DOI: 10.1371/journal.pbio.0050045 full text

56) "Toxoplasma gondii Targets a Protein Phosphatase 2C to the Nucleus of Infected Host Cells" Gilbert, Luke A.; Ravindran, Sandeep; Turetzky, Jay M.; Boothroyd, John C.; Bradley, Peter J. Eukaryotic Cell , 2007, 6, 1, 73-83. DOI:10.1128/EC.00309-06. abstract

55) "Catalytic Intermolecular Amination of C-H Bonds: Method Development and Mechanistic Insights " Kristin W. Fiori, J. Du Bois. Journal of the American Chemical Society, 2007, 129, 3, 562-568. DOI: 10.1021/ja0650450  

54) "Legionella pneumophilia type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung" Sruti DebRoy, Jenny Dao, Maria Soderberg, Ombeline Rossier, Nicholas P. Cianciotto. PNAS, 2006, 103, 50, 19146-19151. DOI: 10.1073/pnas.0608279103  

53) "The C Terminus of the L-Type Voltage-Gated Calcium Channel CaV1.2 Encodes a Transcription Factor" Gomez-Ospina, Natalia; Tsuruta, Fuminori; Barreto-Chang, Odmara; Hu, Linda; Dolmetsch, Ricardo. Cell , 2006, 127, 3, 591-606. DOI: 10.1016/j.cell.2006.10.017. abstract

52) "Site-Specific Conversion of Cysteine Thiols into Thiocyanate Creates an IR Probe for Electric Fields" Fafarman, Aaron T.; Webb, Lauren J.; Chuang, Jessica I.; Boxer, Steven G. Journal of the American Chemical Society , 2006, 128, 41, 13356-13357. DOI: 10.1021/ja0650403 S0002-7863(06)05040-2. abstract

51) "A Rapid, Reversible, and Tunable Method to Regulate Protein Function in Living Cells Using Synthetic Small Molecules" Banaszynski, Laura A.; Chen, Ling-chun; Maynard-Smith, Lystranne A.; Ooi, A.G. Lisa; Wandless, Thomas J. Cell, 2006, 126, 995-1004. abstract

50) "PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane" Heo, Won Do; Inoue, Takanari; Park, Wei Sun; Kim, Man Lyang; Park, Byung Ouk; Wandless, Thomas J.; Meyer, Tobias. Science, 2006, 314, 5804, 1458-1461. abstract

49) "Rh-catalyzed alkene oxidation: a highly efficient and selective process for preparing N-alkoxysulfonyl aziridines" Kiran Guthikonda, Paul M. Wehn, Brian J. Caliando, J. Du Bois. Tetrahedron, 2006, 62, 49, 11331-11342. DOI: 10.1016/j.tet.2006.07.099  

48) "Exploration, Optimization, and Application of Supramolecular Thiourea-Amine Catalysts for the Synthesis of Lactide (Co)polymers" Pratt, Russell C.; Lohmeijer, Bas G.G.; Long, David A.; Lundberg, P.N. Pontus, Dove, Andrew P.; Li, Hongbo; Waymouth, Robert M.; Hedrick, James L. Macromolecules , 2006, 39, 23, 7863-7871. DOI: 10.1128/EC.00309-06. abstract

47) "Entrapment of a dirhodium tetracarboxylate unit inside the aromatic bowl of a calix[4]arene: Unique catalysts for C-H amination. Brodsky, Benjamin H.; DuBois, Justin. Chemical Communications, 2006, 4715-4717. DOI: 10.1039/b611280c. abstract

46) "Azetidine-2-carboxylic acid in garden beets (Beta vulgaris)" Rubenstein, Edward; Zhou, Haihong; Krasinska, Karolina M.; Chien, Allis S.; Becker, Christopher H. Phytochemistry, 2006, 67, 9, 898-903. abstract

45) "Production of Ansamycin Polyketide Precursors in Eschericia coli" Rude, M.A.; Khosla, C. The Journal of Antibiotics, 2006, 59, 8, 464-470. abstract

44) "Single-turnover intermolecular reaction between a Fe(III)-superoxide-Cu(I) cytochrome c oxidase model and exogenous Tyr244 mimics." Collman, James P.; Decreau, Richard A.; Sunderland, Christopher J. Chemical Communications, 2006, 3894-3896. abstract

43) "Proteomic mapping of a suppressor of non-chemotactic cheW mutants reveals that Helicobacter pylori contains a new chemotaxis protein" Terry, Karianne; Go, Alvin C.; Ottemann, Karen M. Molecular Microbiology, 2006, 61, 4, 871-882. abstract

42) "Plasmodium falciparum AMA1 Binds a Rhoptry Neck Protein Homologous to TgRON4, a Component of the Moving Junction in Toxoplasma gondii" Alexander, David L.; Arastu-Kapur, Shirin; Dubremetz, Jean-Francois; Boothroyd, John C. Eukaryotic Cell , 2006, 5, 7, 1169-1173. abstract

41) "Effect of Barley Endoprotease EP-B2 on Gluten Digestion in the Intact Rat" Gass, Jonathan; Vora, Harmit; Bethune, Michael T.; Gray, Gary M.; Khosla, Chaitan. Journal of Pharmacology and Experimental Therapeutics, 2006, 318, 1178-1186. abstract

40) "Identification of differentially regulated proteins in response to a compatible interaction between the pathogen Fusarium graminearum and its host, Triticum aestivum" Zhou, Wenchun; Eudes, Francois; Laroche, Andre. Proteomics, 2006, 6, 16, 4599-4609. abstract

39) "Proteolysis of the replication checkpoint protein Sda is necessary for the efficient initiation of sporulation after transient replication stress in Bacillus subtilis" Ruvolo, Michael V.; Mach, Kathleen E.; Burkholder, William F. Molecular Microbiology, 2006, 60, 6, 1490-1508. abstract

38) "Genomic and Proteomic Analyses of the Agarolytic System Expressed by Saccharophagus degradans 2-40" Ekborg, Nathan A.; Taylor, Larry E.; Longmire, Atkinson G.; Henrissat, Bernard; Weiner, Ronald M.; Hutcheson, Steven W. Applied and Environmental Microbiology, 2006, 72, 5, 3396-3405. abstract

37) "Complete Cellulase System in the Marine Bacterium Saccharophagus degradans Strain 2-40" Taylor, Larry E. II; Henrissat, Bernard; Coutinho, Pedro M.; Ekborg, Nathan A.; Hutcheson, Steven W.; Weiner, Ronald M. Journal of Bacteriology, 2006, 188, 11, 3849-3861. abstract

36) "Synthesis and PCK Binding of a New Class of A-Ring Diversifiable Bryostatin Analogues Utilizing a Double Asymmetric Hydrogenation and Cross-Coupling Strategy" Wender, Paul A.; Horan, Joshua C. Organic Letters , 2006, 8, 20, 4581-4584. abstract

35) "Heterologous Expression, Purification, Refolding, and Structural-Functional Characterization of EP-B2, a Self-Activating Barley Cysteine Endoprotease" Bethune, Michael T.; Strop, Pavel; Tang, Yinyang; Sollid, Ludvig M.; Khosla, Chaitan. Chemistry & Biology , 2006, 13, 637-647. abstract

34) "Control of Formation and Cellular Detachment from Shewanella oneidensis MR-1 Biofilms by Cyclic di-GMP" Thormann, Kai M.; Duttler, Stefanie; Saville, Renee M.; Hyodo, Mamoru; Shukla, Soni; Hayakawa, Yoshihiro; Spormann, Alfred M. Journal of Bacteriology, 2006, 188, 7, 2681-2691. abstract

33) "Rapamycin Analogs with Differential Binding Specificity Permit Orthogonal Control of Protein Activity" Bayle, J. Henri; Grimley, Joshua S.; Stankunas, Kryn; Gestwicki, Jason E.; Wandless, Thomas J.; Crabtree, Gerald R. Chemistry and Biology, 2006, 13, 99-107. abstract

32) "The Bacillus subtilis spore coat protein interaction network" Kim, Hosan; Hahn, Marlene; Grabowski, Paul; McPherson, Derrell; Otte, Michele M.; Wang, Rong; Ferguson, Caitlin C.; Eichenberger, Patrick; Driks, Adam. Molecular Microbiology , 2006, 59, 2, 487-502. abstract

31) "Evaluation of auxin-responsive genes in soybean for detection of off-target plant growth regulator herbicides" Kelley, Kevin B.; Zhang, Qin; Lambert, Kris N.; Riechers, Dean E. Weed Science, 2006, 54, 2, 220-229. abstract

30) "Endopolyphosphatase in Saccharomyces cerevisiae undergoes post-translational activations to produce short-chain polyphosphates" Xiaobing Shi, Arthur Kornberg. FEBS Letters, 2005, 579, 9, 2014-2018. DOI: 10.1016/j.febslet.2005.02.032

29) "A Synthesis of (+)-Saxitoxin" James J. Fleming, J. Du Bois. Journal of the American Chemical Society, 2006, 128, 12, 3926-3927. DOI: 10.1021/ja0608545

28) "Cytochrome c conformations resolved by the photon counting histogram: Watching the alkaline transition with single-molecule sensitivity" Perroud, Thomas D.; Bokoch, Michael P.; Zare, Richard N. PNAS, 2005, 102, 49, 17570-17575. abstract

27) "Identification of the Moving Junction Complex of Toxoplasma gondii: A Collaboration between Distinct Secretory Organelles" Alexander, David L.; Mital, Jeffrey; Ward, Gary E.; Bradley, Peter; Boothroyd, John C. PLoS Pathogens, 2005, 1(2): e17. full text

26) "Differential accumulation of maysin and rhamnosylisoorientin in leaves of high-altitude landraces of maize after UV-B exposure" Casati, Paula; Walbot, Virginia. Plant, Cell & Environment, 2005, 28, 6, 788-799. abstract

25) "Identification of proteins induced or upregulated by Fusarium head blight infection in the spikes of hexaploid wheat (Triticum aestivum)" Zhou, Wenchun; Kolb, Frederic L.; Riechers, Dean E. Genome, 2005, 48, 770-780. abstract

24) "5,10,15-Tris(o--aminophenyl) Corrole (TAPC) as a Versatile Synthon for the Preparation of Corrole-Based Hemoprotein Analogs" Collman, James P.; Decreau, Richard A.. Organic Letters, 2005, 7, 6, 975-978. abstract

23) "Ehrlichia chaffeensis Expresses Macrophage- and Tick Cell-Specific 28-Kilodalton Outer Membrane Proteins" Singu, Vijayakrishna; Liu, Haijie; Cheng, Chuanmin; Ganta, Roman R. Infection and Immunity, 2005, 73, 1, 79-87. abstract

22) "Engineered Biosynthesis of Alkanoic Acid Analogues" Lee, Taek Soon; Khosla, Chaitan; Tang, Yi. Journal of the American Chemical Society, 2005, 127, 35, 12254-12262. abstract

21) "Prolyl Endopeptidase-Mediated Destruction of T Cell Epitopes in Whole Gluten: Chemical and Immunological Characterization" Marti, Thomas; Molberg, Oyvind; Li, Qing; Gray, Gary M.; Khosla, Chaitan; Sollid, Ludvig M. Journal of Pharmacology and Experimental Theraperutics, 2005, 312, 19-26. abstract

20) "Synthesis of (4-[18F]fluorophenyl)triphenylphosphonium as a potential imaging agent for mitochondrial dysfunction" Cheng, Zhen; Subbarayan, Murugesan; Chen, Xiaoyuan; Gambhir, Sanjiv Sam. Journal of Labelled Compounds and Radiopharmaceuticals, 2005, 48, 131-137. abstract

19) "Leukemia Proto-Oncoprotein MLL Forms a SET1-Like Histone Methyltransferase Complex with Menin to Regulate Hox Gene Expression " Yokoyama, Akihiko; Wang, Zhong; Wysocka, Joanna; Sanyal, Mrinmoy; Aufiero, Deborah J.; Kitabayashi, Issay; Herr, Winship; Cleary, Michael L. Molecular and Cellular Biology, 2004, 24, 13, 5639-5649. abstract

18) "Proteomic Characterization of Herbicide Safener-induced Proteins in the Coleoptile of Triticum tauschii seedlings" Zhang, Qin; Riechers, Dean E. Proteomics, 2004, 4, 2058-2071. abstract

17) "Crosslinking of Ribosomal Proteins to RNA in Maize Ribosomes by UV-B and Its Effects on Translation" Casati, Paula; Walbot, Virginia. Plant Physiology, 2004, 136, 3319-3332. abstract

16) "Regulation of Antiprotease and Antimicrobial Protein Secretion by Airway Submucosal Gland Serous Cells" Joo, Nam Soo; Lee, Dennis J.; Winges, Kimberly M.; Rustagi, Arjun; Wine, Jeffrey J. Journal of Biological Chemistry, 2004, 279, 37, 38854-38860. abstract

15) "Synthesis of Cytochrome c Oxidase Models Bearing a Tyr-244 Mimic" Collman, James P.; Decreau, Richard A.; Zhang, Chi. Journal of Organic Chemistry, 2004, 69, 3546-3549. abstract
14) "Appending a Tris-imidazole Ligand with a Tyr-244 Mimic on the Distal Face of Bromoacetamidoporphyrin" Collman, James P.; Decreau, Richard A.; Costanzo, Simona. Organic Letters, 2004, 6, 6, 1033-1036. abstract

13) "Comparative Biochemical Analysis of Three Bacterial Prolyl Endopeptidases: Implications for Celiac Sprue" Shan, Lu; Marti, Thomas; Sollid, Ludvig M.; Gray, Gary M; Khosla, Chaitan. Biochemical Journal, 2004, 383, 311-318. abstract

12) "Exploring the biosynthetic potential of bimodular aromatic polyketide synthases"Tang, Yi; Lee, Taek Soon; Lee, Ho Young; Khosla, Chaitan. Tetrahedron, 2004, 60, 35, 7659-7671. abstract

11) "Engineered Biosynthesis of Regioselectively Modified Aromatic Polyketides Using Bimodular Polyketide Synthases" Tang, Yi; Lee, Taek Soon; Khosla, Chaitan. PLoS Biology , 2004, 2(2): e31. full text

10) "Reconstituting Modular Activity from Separated Domains of 6-Deoxyerythronolide B Synthase" Kim, Chu-Young; Alekseyev, Viktor Y.; Chen, Alice Y.; Tang, Yinyan; Cane, David E.; Khosla, Chaitan. Biochemistry, 2004, 43, 13892-13898. abstract

9) "S-crystallin and arginine kinase bind F-actin in light- and dark-adapted octopus retinas" Zuniga, Freddi Isaac; Ochoa, Gina H.; Kelly, Shannon D.; Robles, Laura J. Current Eye Research , 2004, 38, 5, 343-350. abstract

8) "The Function of Hydrophobic Residues in the Catalytic Cleft of Streptococcus pneumoniae Hyaluronate Lyase" Nukui, masatoshi; Taylor, Kenneth B.; McPherson, David T.; Shigenaga, Mark K.; Jedrzejas, Mark J. Journal of Biological Chemistry , 2003, 278, 5, 3079-3088. abstract

7) "Ketosynthases in the Initiation and Elongation Modules of Aromatic Polyketide Synthases have Orthogonal Acyl Carrier Protein Specificity" Tang, Yi; Lee, Taek Soon; Kobayashi, Seiji; Khosla, Chaitan. Biochemistry, 2003, 42, 6588-6595. abstract

6) "Biosynthesis of Yersiniabactin, a Complex Polyketide-Nonribosomal Peptide, Using Escherichia coli as a Heterologous Host " Pfeifer, Blaine A.; Wang, Clay C.C.; Walsh, Christopher T.; Khosla, Chaitan. Applied and Environmental Microbiology, 2003, 69, 11, 6698-6702. abstract

5) "Engineered Biosynthesis of an Ansamycin Polyketide Precursor in Escherichia Coli" Watanabe, Kenji; Rude, Matthew A.; Walsh, Christopher T.; Khosla, Chaitan. Proceedings of the National Academy of Sciences of the U.S., 2003, 100, 17, 9774-9778. abstract
4) "Rapid Mapping of Protein Structure, Interactions, and Ligand Binding by Misincorporation Proton-Alkyl Exchange" Silverman, Joshua A.; Harbury, Pehr. Journal of Biological Chemistry, 2002, 277, 34, 30968-30975. abstract

3) "Structural Basis for Gluten Intolerance in Celiac Sprue" Shan, Lu; Molberg, Oyvind; Parrott, Isabelle; Hausch, Felix; Filiz, Ferda; Gray, Gary M.; Sollid, Ludwig M.; Khosla, Chaitan. Science, 2002, 297, 2275-2279. abstract

2) "Intestinal digestive resistance of immunodominant gliadin peptides" Hausch, Felix; Shan, Lu; Santiago, Nilda A.; Gray, Gary M.; Khosla, Chaitan. American Journal of Physiology - Gastrointestinal & Liver Physiology, 2002, 283, G996-G1003. abstract

1) "Malonyl-CoA:ACP Transacylase from Streptomyces coelicolor Has Two Alternative Catalytically Active Nucleophiles" Dreier, Juerg; Li, Qing; Khosla, Chaitan. Biochemistry, 2001, 40, 12407-12411. abstract

 

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